Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

SIADH) is a condition that happens when your body makes too much antidiuretic hormone (also called "ADH"). ADH helps manage the amount of water in your body. If you have too much ADH, your kidneys cant get rid of water. Fluid builds up in your body and dilutes the amount of salt in your blood. This causes a condition called "hyponatremia. " пїЅ пїЅ пїЅ

What causes SIADH? " пїЅ Many things can cause SIADH, including: пїЅ пїЅ

Medicines " пїЅ These include medicines used to treat type 2 diabetes, high blood pressure, seizures, and cancer.
Infections such as pneumonia
Surgery, especially on the bones and joints
Brain and spinal cord problems " пїЅ This includes strokes, bleeding, or an infection in your brain.
Cancer " пїЅ This includes different types of lung cancer (especially small cell) and cancer of the stomach, pancreas, or brain.

What are the symptoms of SIADH? " пїЅ The symptoms are the same as the symptoms of hyponatremia and include: пїЅ пїЅ

Nausea and vomiting
Headache
Confusion or trouble thinking clearly
Feeling weak or tired
Feeling restless or irritable
Muscle weakness, spasms or cramps
Seizures or passing out

Is there a test for SIADH? " пїЅ Yes. Tests include blood and urine tests. пїЅ пїЅ

How is SIADH treated? " пїЅ That depends on what is causing your SIADH. For example, if you have an infection, your doctor might prescribe medicines to treat it. He or she might also tell you to: пїЅ пїЅ

Limit the amount of fluids you drink
Eat salt tablets or get a salt-water solution into a vein
Stop taking a medicine that is causing the problem

All topics are updated as new evidence becomes available and our peer review process is complete. пїЅ пїЅ

This topic retrieved from UpToDate on: Nov 04, 2014. пїЅ пїЅ

Topic 86640 Version 2.0 пїЅ пїЅ

Release: 22.8 - C22.208 пїЅ пїЅ

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Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

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