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Abdominal Adhesions

para>Small bowel obstructions in patients without a history of abdominal surgery should not be routinely ascribed to adhesive disease without further workup, to exclude obstruction due to malignancy or other processes (4)[C].  

HISTORY


  • Prior abdominal surgery
  • History of abdominal infection or pelvic inflammatory disease
  • Bowel complaints may include:
    • Crampy abdominal pain
    • Nausea, vomiting
    • Minimal to no flatus
    • Loud bowel sounds (borborygmi)
    • Abdominal distension
  • If involving a pelvic structure, complaints may include:
    • Lower abdominal pain (either chronic or acute)
    • Infertility
    • Nausea/vomiting

PHYSICAL EXAM


  • Vital sign abnormalities (evidence of ischemia, dehydration, or infection)
  • Fever
  • Tachycardia
  • Diffuse abdominal tenderness
  • Peritoneal signs: guarding, rebound, rigidity
  • Abdominal scars
  • In the case of small bowel obstruction:
    • Abdominal distention
    • Tympany
    • Altered bowel sounds

DIAGNOSTIC TESTS & INTERPRETATION


Initial Tests (lab, imaging)
  • No lab or imaging tests definitively demonstrate adhesions. Workup should include WBC, lactate, electrolytes, BUN/creatinine
  • Imaging modalities such as supine and erect abdominal x-ray (4)[B], water-soluble oral-contrasted CT scan (4)[B], and water-soluble contrast follow-through can help diagnose small bowel obstruction (SBO) (4)[A].

TREATMENT


SURGERY/OTHER PROCEDURES


  • Nasogastric decompression for patients with evidence of partial SBO without specific indications for surgery (4)[A]
  • Adhesiolysis
    • Performed for symptomatic complications of adhesions, although criteria for surgery in these cases depends on the specific complication
      • Indications for adhesiolysis in setting of SBO include signs of strangulation or peritonitis, surgery within 6 weeks, carcinomatosis, irreducible hernia, no signs of resolution within 72 hours (4)[A].
      • With adhesiolysis, there is always the risk of new adhesions.
  • Laparoscopic: primarily for pelvic adhesions
    • Appropriate for highly selected patient (4)[B]
    • May be most effective in removing abdominal wall adhesions and least effective for adnexal adhesions (5)[C]
    • Helps treat chronic pelvic pain only when severe
  • Open: primarily for peritoneal adhesions
    • Laparotomy is the preferred surgical resolution to SBO related to adhesions in cases of failed conservative management (4)[B].

ONGOING CARE


PROGNOSIS


  • Adhesions are typically asymptomatic. Once present, they cannot be fully removed.
  • No single approach has been satisfactory in removing adhesions.

COMPLICATIONS


  • Most common complication is bowel obstruction (either partial or complete)
  • Chronic pelvic pain
  • Infertility
  • Surgical complications:
    • Prolonged surgery
    • Intraoperative bleeding
    • Trocar injury (adhesions to ventral abdominal wall)
    • Conversion of laparoscopy to laparotomy
    • Inadvertent enterotomy or other organ damage
    • Prolonged length of hospital stay
    • Postoperative morbidity/mortality is slightly higher than virgin abdomen.

REFERENCES


11 Arung  W, Meurisse  M, Detry  O. Pathophysiology and prevention of postoperative peritoneal adhesions. World J Gastroenterol.  2011;17(41):4545-4553.22 Robb  WB, Mariette  C. Strategies in the prevention of the formation of postoperative adhesions in digestive surgery: a systematic review of the literature. Dis Colon Rectum.  2014;57(10):1228-1240.33 van der Wal  JB, Iordens  GI, Vrijland  WW, et al. Adhesion prevention during laparotomy: long-term follow-up of a randomized clinical trial. Ann Surg.  2011;253(6):1118-1121.44 Di Saverio  S, Coccolini  F, Galati  M, et al. Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2013 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group. World J Emerg Surg.  2013;8(1):42.55 Ward  BC, Panitch  A. Abdominal adhesions: current and novel therapies. J Surg Res.  2011;165(1):91-111.

ADDITIONAL READING


  • Blumenfeld  YJ, Caughey  AB, El-Sayed  YY, et al. Single-versus double-layer hysterotomy closure at primary caesarean delivery and bladder adhesions. BJOG.  2010;117(6):690-694.
  • Diamond  MP, Burns  EL, Accomando  B, et al. Seprafilm( ®) adhesion barrier: (2) a review of the clinical literature on intraabdominal use. Gynecol Surg.  2012;9(3):247-257.
  • Dupr ©  A, Lefranc  A, Buc  E, et al. Use of bioresorbable membranes to reduce abdominal and perihepatic adhesions in 2-stage hepatectomy of liver metastases from colorectal cancer: results of a prospective, randomized controlled phase II trial. Ann Surg.  2013;258(1):30-36.
  • Esposito  AJ, Heydrick  SJ, Cassidy  MR, et al. Substance P is an early mediator of peritoneal fibrinolytic pathway genes and promotes intra-abdominal adhesion formation. J Surg Res.  2013;181(1):25-31.
  • Hackethal  A, Sick  C, Szalay  G, et al. Intra-abdominal adhesion formation: does surgical approach matter? Questionnaire survey of South Asian surgeons and literature review. J Obstet Gynaecol Res.  2011;37(10):1382-1390.
  • Hellebrekers  BW, Kooistra  T. Pathogenesis of postoperative adhesion formation. Br J Surg.  2011;98(11):1503-1516.
  • Lauder  CI, Garcea  G, Strickland  A, et al. Abdominal adhesion prevention: still a sticky subject? Dig Surg.  2010;27(5):347-358.
  • Oua ¯ssi  M, Gaujoux  S, Veyrie  N, et al. Post-operative adhesions after digestive surgery: their incidence and prevention: review of the literature. J Visc Surg.  2012;149(2):e104-e114.

SEE ALSO


Algorithm: Intestinal Obstruction; Infertility  

CODES


ICD10


  • K66.0 Peritoneal adhesions (postprocedural) (postinfection)
  • Q43.3 Congenital malformations of intestinal fixation
  • N99.4 Postprocedural pelvic peritoneal adhesions
  • N73.6 Female pelvic peritoneal adhesions (postinfective)

ICD9


  • 568.0 Peritoneal adhesions (postoperative) (postinfection)
  • 751.4 Anomalies of intestinal fixation
  • 614.6 Pelvic peritoneal adhesions, female (postoperative) (postinfection)

SNOMED


  • adhesion of abdominal wall (disorder)
  • peritoneal adhesion (disorder)
  • Congenital intestinal adhesions (disorder)
  • Postprocedural pelvic peritoneal adhesions (disorder)
  • Female pelvic peritoneal adhesions
  • Adhesion of intestine (disorder)

CLINICAL PEARLS


  • Abdominal adhesions result primarily from abdominal infection or trauma (including surgery).
  • Most adhesions are asymptomatic; the most common complication is bowel obstruction (partial or complete).
  • The degree of pain does not correlate with the number of adhesions.
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