Protein, Cerebrospinal Fluid

Doctor123.org helps physicians and healthcare professionals Diseases & Conditions Drugs Patient Handouts Procedures Lab Tests Protein, Cerebrospinal Fluid Definition CSF protein concentration is one of the most sensitive indicators of pathology within the CNS. Normal range: 15 " “45 mg/dL. Use To detect increased permeability of the blood " “brain barrier to plasma proteins To detect increased intrathecal production of immunoglobulins Interpretation Increased In Bacterial meningitis Brain tumor Brain abscess Aseptic meningitis Multiple sclerosis Cerebral hemorrhage Epilepsy Acute alcoholism Neurosyphilis Decreased In Repeated lumbar puncture or a chronic leak, in which CSF is lost at a higher than normal rate Some children between the ages of 6 months and 2 years Acute water intoxication Minority of patients with idiopathic intracranial hypertension Limitations CSF protein levels do not fall in hypoproteinemia. The normal reference ranges is somewhat technique dependent and vary from laboratory to laboratory. Excessive amounts of CSF proteins are seen in Froin syndrome, clotted specimens, xanthochromia, or the presence of free blood. In premature infants, values >130 mg/dL may occasionally be observed. Copyright © 2016 - 2017 Doctor123.org | Disclaimer