The Basics
Written by the doctors and editors at UpToDate
What is calcium pyrophosphate deposition disease? " Calcium pyrophosphate deposition disease, also called CPPD, is a type of arthritis that causes sudden attacks of joint pain and swelling. It is caused by a build-up of a type of calcium crystals (called "calcium pyrophosphate " ) in the joints. CPPD used to be called pseudogout.
The symptoms of CPPD are similar to the symptoms of another type of arthritis, called gout. But CPPD and gout have different causes.
What are the symptoms of CPPD? " People with CPPD get sudden attacks of joint pain, swelling, and warmth " often in the knee. The symptoms can also happen in the ankles, feet, shoulders, elbows, wrists, and hands. Attacks can last for days or weeks.
In some people, CPPD leads to long-term osteoarthritis. Osteoarthritis is the most common type of arthritis. It causes pain and stiffness in different joints in the body. Sometimes it also causes joint swelling.
Is there a test for CPPD? " Yes. To check if your symptoms are caused by CPPD, your doctor will do an exam and tests. Tests can include:
- Removing fluid from the painful joint " A doctor will put a needle in the joint to remove a small sample of fluid. Then he or she will look at the fluid under a microscope to see if the calcium crystals are present.
- X-rays of the painful joints
- Blood tests " Your doctor will do blood tests to see if you have a condition that could be causing the calcium crystals to build up.
How is CPPD treated? " Treatment often depends on how many joints are involved.
Doctors usually treat people who have 1 or 2 painful joints by:
- Removing some fluid from the painful joint
- Giving a shot of a medicine into the painful joint
Doctors usually treat people who have more than 2 painful joints with medicines called "NSAIDs. " NSAIDs are a large group of medicines that includes ibuprofen (sample brand names: Advil, Motrin), indomethacin (sample brand names: Indocin, Indocid), and naproxen (sample brand names: Aleve, Naprosyn). If a person cant take NSAIDs or has too many side effects from NSAIDs, other types of medicines are available.
All of these treatments for CPPD help to shorten an attack and ease joint pain and swelling.
Is there anything I can do on my own? " Yes. Doctors usually recommend that people rest their painful joints as much as possible when an attack happens. If your doctor recommends rest, try not to move your painful joint or put weight on it.
Can CPPD attacks be prevented? " Sometimes. If you get a lot of attacks, your doctor might prescribe a medicine for you to take every day to help prevent future attacks. This medicine is called colchicine (brand name: Colcrys).
All topics are updated as new evidence becomes available and our peer review process is complete.
This topic retrieved from UpToDate on: Nov 04, 2014.
Topic 16267 Version 5.0
Release: 22.8 - C22.206
© 2014 UpToDate, Inc. All rights reserved.
Consumer Information Use and Disclaimer
This information is not specific medical advice and does not replace information you receive from your health care provider. This is only a brief summary of general information. It does NOT include all information about conditions, illnesses, injuries, tests, procedures, treatments, therapies, discharge instructions or life-style choices that may apply to you. You must talk with your health care provider for complete information about your health and treatment options. This information should not be used to decide whether or not to accept your health care providers advice, instructions or recommendations. Only your health care provider has the knowledge and training to provide advice that is right for you.The use of UpToDate content is governed by the UpToDate Terms of Use. ©2014 UpToDate, Inc. All rights reserved.
Copyright
© 2014 UpToDate, Inc. All rights reserved.