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Fecal Fat


Definition


  • Test for steatorrhea or excess fat in bowel movements due to fat. Helps to estimate the percentage of dietary fat that the body does not absorb
  • Normal range: <7 g of fat per 24 hours

Use


  • Aids in the diagnosis of malabsorption
  • As a follow-up to other stool tests and blood tests to investigate the cause of chronic diarrhea and loose, fatty, foul-smelling stools (steatorrhea)

Interpretation


  • A person who consumes 100 g of fat per day would have an average stool fat of <7 g/24 hours. Fecal excretion of more than 7 g of fat in a 24-hour period or more than 7% of the measured fat intake over a 3-day period is indicative of fat malabsorption or steatorrhea malabsorption.

Increased In


  • The absence or significant decrease of the pancreatic enzymes, amylase, lipase, trypsin, and chymotrypsin limits fat, protein, and carbohydrate digestion, resulting in steatorrhea due to fat malabsorption.
  • The underlying condition of steatorrhea includes
    • Celiac disease
    • Chronic pancreatitis
    • Crohn disease
    • Cystic fibrosis
    • Gallstones (cholelithiasis)
    • Pancreatic cancer
    • Pancreatitis

Decreased In


  • NA

Limitations


  • For a 72-hour stool collection, 50 " “150 g of fat a day for 2 " “3 days prior to and during the stool collection period needs to be consumed. The fat should be long-chain triglycerides (such as corn or olive oil, not butter).
  • False-positive results can occur due to mineral oil or castor oil present in the specimen.
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