Use
- This test is used to evaluate diarrheal disease in patients at risk for cryptosporidiosis, specifically for the identification of Cryptosporidium parvum in stool specimens.
- Method:
- Enzyme immunoassays are used. EIAs have very high sensitivity (near 100%) and specificity (near 100%) compared with a series of stool O & P examinations. For information about microscopic Cryptosporidium detection, see the test Ova and Parasite Examination, Stool.
- Different EIA assays for fecal parasite detection have different specimen requirements (fresh vs. preserved) and transport conditions. Laboratories should provide assay-specific information for their providers.
- Turnaround time: 24 " “48 hours
Interpretation
- Expected results: Negative.
Limitations
- Examination of several specimens improves detection in patients with light infection. A series of O & P examinations is recommended in patients with repeatedly negative immunoassays in whom parasitic infection is still suspected.
Suggested Readings
1CLSI. Procedures for the Recovery and Identification of Parasites from the Intestinal Tract; Approved Guideline, 2nd ed. CLSI document M47-A. Wayne, PA: Clinical and Laboratory Standards Institute; 2005. 2Garcia ‚ LS. Diagnostic Parasitology, 5th ed. Washington, DC: ASM Press; 2007.