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Eosinophilic Pneumonias

para>More morbidity in the elderly, probably owing to decreased lung capacity and likelihood of concomitant diseases  

COMPLICATIONS


  • Some patients may show evidence of dysfunction in the small airways.
  • Delay in treatment of tropical pulmonary eosinophilia may result in irreversible pulmonary fibrosis.
  • Steroid complications especially when used long-term such as osteoporosis and increased risk of infections

REFERENCES


11 Fern ¡ndez P ©rez  ER, Olson  AL, Frankel  SK. Eosinophilic lung diseases. Med Clin North Am.  2011;95(6):1163-1187.22 Li  H, Groshong  SD, Lynch  D, et al. Eosinophilic lung disease. Clin Pulm Med.  2010;17(2):66-74.33 Groh  M, Pagnoux  C, Baldini  C, et al. Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EPGA) Consensus Task Force recommendations for evaluation and management. Eur J Intern Med.  2015;26(7):545-553.44 Soubani  AO, Chandrasekar  PH. The clinical spectrum of pulmonary aspergillosis. Chest.  2002;121(6):1988-1999.55 Philit  F, Etienne-Mastro ¯ni  B, Parrot  A, et al. Idiopathic acute eosinophilic pneumonia: a study of 22 patients. Am J Respir Crit Care Med.  2002;166(9):1235-1239.66 Jeong  YJ, Kim  KI, Seo  IJ, et al. Eosinophilic lung diseases: a clinical, radiologic, and pathologic overview. Radiographics.  2007;27(3):617-637.77 Furuiye  M, Yoshimura  N, Kobayashi  A, et al. Churg-Strauss syndrome versus chronic eosinophilic pneumonia on high-resolution computed tomographic findings. J Comput Assist Tomogr.  2010;34(1):19-22.88 Marchand  E, Reynaud-Gaubert  M, Lauque  D, et al. Idiopathic chronic eosinophilic pneumonia. A clinical and follow-up study of 62 cases. The Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires (GERM"O"P). Medicine (Baltimore).  1998;77(5):299-312.99 Rhee  CK, Min  KH, Yim  NY, et al. Clinical characteristics and corticosteroid treatment of acute eosinophilic pneumonia. Eur Respir J.  2013;41(2):402-409.1010 Jhun  BW, Kim  SJ, Son  RC, et al. Clinical outcomes in patient with acute eosinophilic pneumonia not treated with corticosteroids. Lung.  2015;193(3):361-367.1111 Stevens  DA, Schwartz  HJ, Lee  JY, et al. A randomized trial of itraconazole in allergic bronchopulmonary aspergillosis. N Engl J Med.  2000;342(11):756-762.1212 Akuthota  P, Weller  PF. Eosinophilic pneumonias. Clin Microbiol Rev.  2012;25(4):649-660.

ADDITIONAL READING


  • Alam  M, Burki  NK. Chronic eosinophilic pneumonia: a review. South Med J.  2007;100(1):49-53.
  • Grau  RG. Churg-Strauss syndrome: 2005-2008 update. Curr Rheumatol Rep.  2008;10(6):453-458.
  • Janz  DR, O'Neal  HRJr, Ely  EW. Acute eosinophilic pneumonia: a case report and review of the literature. Crit Care Med.  2009;37(4):1470-1474.
  • Rossi  G, Tironi  A, Dore  R, et al. Pulmonary eosinophilic infiltrates. Pathologica.  2010;102(6):537-546.

SEE ALSO


Aspergillosis; Roundworms, Tissue; Tuberculosis; Wegener Granulomatosis  

CODES


ICD10


J82 Pulmonary eosinophilia, not elsewhere classified  

ICD9


518.3 Pulmonary eosinophilia  

SNOMED


  • Pulmonary eosinophilia (disorder)
  • lfflers syndrome (disorder)
  • Asthmatic pulmonary eosinophilia (disorder)

CLINICAL PEARLS


  • Eosinophilic pneumonias are not common.
  • They are classified as either acute or chronic and can be either idiopathic or secondary to other causes.
  • Bronchoscopy with bronchoalveolar lavage is useful for diagnosis.
  • Corticosteroid therapy is dramatically effective.
  • Other treatments are based on secondary etiologies.
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