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Speech Delay, Pediatric


Basics


Description


  • Speech delay is delay in the acquisition of spoken language.
  • Language is a system of symbols through which humans communicate thoughts, feelings, and ideas. It has 3 components " ”receptive, expressive, and visual language.
    • Receptive language is the ability to process and understand language.
    • Expressive language is the ability to communicate through speech, written, or formal sign language.
    • Visual elements include eye contact, pointing, and gestures.
  • Speech delay can be primary as in specific language impairment (SLI) or developmental language disorder (DLD), or secondary to another condition such as a syndrome or neurologic disorder. SLI is impaired speech/language in an otherwise normally developing child who lacks signs or stigmata of other conditions.
  • Constitutional language delay, a retrospective diagnosis, is language delay associated with eventual achievement of normal speech and language milestones by school age. There are no subsequent difficulties with learning to read or write.
  • Expressive language disorders include the following:
    • Verbal dyspraxia: little speech produced with great effort, very dysfluent, single words most commonly
    • Speech programming deficit disorder: poorly organized, difficult-to-understand speech
  • Mixed receptive and expressive disorders
    • Verbal auditory agnosia: impaired ability to decode speech, resulting in a severe expressive impairment. Can often learn language visually
    • Phonologic/syntactic deficit disorder: most common type of DLD. Comprehension exceeds spoken ability. Speech is dysfluent, grammatically incorrect with short utterances.
    • Most frequent causes of speech delay:
      • Hearing loss
      • SLI
      • Autism spectrum disorder
      • Intellectual disability (formerly mental retardation)

Epidemiology


  • Up to 15% of 2-year-old have speech and language delays.
  • 5% of school-aged children have speech and language delays.
  • 3:1 male-to-female ratio in DLD

Risk Factors


  • Family history of speech/language delay or disorder
  • Male gender
  • Low maternal education
  • Maternal depression
  • Prematurity
  • Birth weight <1,000 g

Diagnosis


Differential Diagnosis


  • Hearing loss
    • Isolated genetic hearing loss
    • Hearing loss secondary to in utero cytomegalovirus (CMV) infection: full syndrome at birth or asymptomatic infection with delayed onset of progressive hearing loss
    • Acquired hearing loss: following head trauma, tumor-associated, complication of bacterial meningitis, end result of frequent acute otitis media or chronic otitis media with effusion
  • Intellectual disability
  • Autism spectrum disorder
  • SLI
  • Constitutional language delay
  • Selective mutism
  • Environmental
    • Lack of stimulation and/or poor linguistic environment
    • Child abuse or neglect
    • Lead poisoning
  • Congenital
    • Cerebral palsy
    • Hydrocephalus
    • Down syndrome
    • Fragile X syndrome
    • 22q11 microdeletion syndrome
    • Fetal alcohol syndrome
    • Turner syndrome
    • Klinefelter syndrome
    • Prader-Willi syndrome
    • Angelman syndrome
    • Muscular dystrophy
    • Tuberous sclerosis
    • Neurofibromatosis
    • Williams syndrome
    • Branchio-oto-renal (BOR) syndrome
    • Craniofacial anomalies such as Treacher Collins and Goldenhar syndromes
  • Nutritional
    • Malnutrition
    • Iron deficiency
  • Infectious
    • HIV encephalopathy
    • Other in utero viral infection
    • Congenital toxoplasmosis
    • Congenital syphilis

Alert
  • Avoid late referral of congenital hearing loss: Amplification and therapy by 6 months of age can result in near-normal rate of speech/language acquisition.
  • Constitutional language delay is a retrospective diagnosis. Do not miss a language disorder if assuming a delayed toddler is a "late bloomer. " ¯
  • Avoid overlooking fine or gross motor delays.
  • Avoid missing a genetic or neurologic diagnosis.

History


Does the family note a concern about speech delay or hearing impairment? ‚  
  • Question: Perinatal history?
  • Significance: prenatal care, maternal illness, NICU admission, hyperbilirubinemia requiring exchange transfusion, treatment with ototoxic drugs such as gentamicin, newborn hearing screen results
  • Question: Full developmental history?
  • Significance: to determine if global delay or isolated speech and language delay
  • Question: Parental concern about delayed expressive language?
  • Significance: often the presentation of autism
  • Question: History of feeding, swallowing difficulties, or poor acceptance of textured foods?
  • Significance: signs of oromotor dysfunction which may indicate a neurologic problem
  • Question: Family history of speech delay, hearing loss, neurologic disorder, or syndrome?
  • Significance: may direct further evaluation
  • Question: Any regression or loss of language milestones?
  • Significance: should prompt a neurologic and metabolic workup
  • Question: What is the social interaction of the child?
  • Significance: Lack of interest in playing is a red flag for autism.
  • Question: Any concern regarding child abuse or neglect or psychosocial deprivation?
  • Significance: may have occurred as the result of a parental, genetic, or developmental disorder; drug or alcohol abuse; poverty; child malnutrition; or environmental toxins such as lead
  • Question: History of frequent acute otitis media or otitis media with effusion and conductive hearing loss?
  • Significance: may precede speech delay
  • Question: Visual impairments?
  • Significance: may impact speech development because interpretation of facial expressions and gestures is a component of infant receptive language development
  • Question: History of traumatic brain injury?
  • Significance: Speech delay may occur with a seizure disorder.

Physical Exam


Complete examination looking for signs that may be associated with speech delay. ‚  
  • Finding: Microcephaly?
  • Significance: associated with intellectual disability, in utero CMV infection, or dysmorphic features
  • Finding: Macrocephaly?
  • Significance: associated with hydrocephalus, various syndromes
  • Finding: Dysmorphic features?
  • Significance: suggestive of a syndrome
  • Finding: Excess drooling and open-mouth posture?
  • Significance: signs of poor oral motor control of muscles used for speech production
  • Finding: Craniofacial abnormalities?
  • Significance: Articulation difficulty may be due to velopalatal insufficiency (VPI) seen with unrepaired cleft lip or palate.
  • Finding: Scarred tympanic membranes or middle ear fluid?
  • Significance: may be clue to acquired intermittent or chronic conductive hearing loss
  • Finding: Macroorchidism?
  • Significance: fragile X syndrome
  • Finding: Neurologic exam " ”hypertonia or hypotonia, abnormal reflexes, other focal findings?
  • Significance: suggestive of neurologic impairment
  • Finding: Cafe au lait spots, hypopigmented macules, shagreen patch, axillary or inguinal freckling?
  • Significance: skin findings suggestive of a neurocutaneous syndrome

Diagnostic Tests & Interpretation


  • The American Academy of Pediatrics recommends a specific development screening tool be administered at the 9, 18, and 24 or 30-month well-child care visits and an autism-specific tool be administered at the 18- and 24-month visits.
  • Office development screening tools
    • Denver Developmental Assessment II
  • Early Language Milestone Scale (ELMS)
  • Clinical Linguistic and Auditory Milestone Scale (CLAMS)
  • Hearing evaluation
    • Most states have mandated Universal Newborn Hearing Screening Programs.
    • Screening tests: automated auditory brainstem response (AABR) and transient evoked otoacoustic emissions (OAEs)
    • Hearing should be tested in all speech-delayed children, even if the newborn hearing screen was normal.
    • <6 months of age: The definitive test is brainstem auditory evoked response (BAER).
    • >6 months of age in a neurologically normal child: The definitive test is behavioral audiometry, such as visual reinforcement audiometry (VRA), performed by a trained audiologist.
  • Selected speech/language milestones
    • 2 months: cooing, response to voice
    • 6 months: babbling
    • 4 " “9 months: turns to sound, responds to name
    • 9 months: dada/mama nonspecific, begins to understand "no " ¯
    • 9 " “12 months: jargon
    • 12 months: dada, mama specific, 1 additional word, jargon is complex, points to gesture, follows 1-step command
    • 18 months: 10 words, knows body parts
    • 2 years: 50 words, 2-word phrases, 50% intelligible by strangers, pronouns, can point to specific objects in a picture, may know 1 color, follows 2-step commands
    • 3 years: 300 " “500 words, tells stories, 75% intelligible by strangers
    • 4 years: grammatically correct sentences, 100% intelligible by strangers
  • Routine cranial imaging or screening tests for metabolic diseases are not recommended.
  • Test: Full speech and language evaluation
  • Significance: To delineate the disorder and determine therapy
  • Test: Individuals with Disabilities Education Act (IDEA) mandates early intervention services from birth to 3 years.
  • Significance: Children can get a full developmental evaluation and appropriate therapy if sufficient delays are demonstrated.
  • Test: EEG
  • Significance: Indicated if there is concern for seizures
  • Test: Genetics evaluation
  • Significance: Should be obtained for congenital hearing loss or if there is concern for a syndrome or genetic diagnosis
  • Test: Prolonged sleep EEG
  • Significance: Indicated with loss of language milestones (consider the diagnosis of Landau " “Kleffner syndrome)

Treatment


General Measures


  • Congenital hearing loss is managed by a team consisting of an otolaryngologist, audiologist, and speech/language therapist who individualize management. Options are amplification, cochlear implant for the severely impaired, or use of sign language.
  • Speech and language therapy can be provided through physician referral or parent-generated referral to early intervention programs.
  • Sign language can be used as a bridge to promote communication while the child learns verbal skills. It will not preclude or delay the development of speech.
  • Augmentative communication devices such as picture boards or programmed computers with voice synthesizers can be used by children with physical impairments such as cerebral palsy.
  • Children with DLD usually speak adequately by school age. Some percentage will go on to have difficulty reading and writing.
  • Children with constitutional language delay will achieve normal milestones by school entrance without reading disability or other learning problem.

Additional Reading


  • Agin ‚  M. The "late talker " ¯ " ”when silence isn 't golden. Contemp Pediatr.  2004;21:22 " “32.
  • Campbell ‚  T, Dollaghan ‚  C, Rockette ‚  H, et al. Risk factors for speech delay of unknown origin in 3-year old children. Child Dev.  2003;74(2):346 " “357. ‚  [View Abstract]
  • Coplan ‚  J. Normal speech and language development: an overview. Pediatr Rev.  1995;16(3):91 " “100. ‚  [View Abstract]
  • Feldman ‚  H. Evaluation and management of language and speech disorders in preschool children. Pediatr Rev.  2005;26(4):131 " “140. ‚  [View Abstract]
  • Rapin ‚  I. Practitioner review: developmental language disorders: a clinical update. J Child Psychol Psychiatry.  1996;37(6):643 " “655. ‚  [View Abstract]
  • Sokol ‚  J, Hyde ‚  M. Hearing screening. Pediatr Rev.  2002;23(5):155 " “162. ‚  [View Abstract]

Codes


ICD09


  • 315.39 Other developmental speech disorder
  • 315.34 Speech and language developmental delay due to hearing loss
  • 315.31 Expressive language disorder
  • 315.32 Mixed receptive-expressive language disorder
  • 315.35 Childhood onset fluency disorder
  • 784.59 Other speech disturbance

ICD10


  • F80.9 Developmental disorder of speech and language, unspecified
  • F80.4 Speech and language development delay due to hearing loss
  • F80.1 Expressive language disorder
  • F80.2 Mixed receptive-expressive language disorder
  • F80.0 Phonological disorder
  • R47.9 Unspecified speech disturbances
  • F80.81 Childhood onset fluency disorder
  • F80.89 Other developmental disorders of speech and language

SNOMED


  • 229721007 speech delay (disorder)
  • 441719005 Speech and language developmental delay due to hearing loss (disorder)
  • 229734008 Expressive language delay (disorder)
  • 702528003 Developmental delay in receptive-expressive language (disorder)
  • 62221000119105 Severe expressive language delay (disorder)
  • 62231000119108 Mild expressive language delay (disorder)
  • 62415009 Delayed articulatory and language development (finding)
  • 62211000119103 Moderate expressive language delay (disorder)

FAQ


  • Q: Do 2nd- and 3rd-born children speak later than 1st-born children?
  • A: No. The norms for expected speech/language development are the same regardless of birth order. 2nd- and 3rd-born children should have the same degree of motivation to speak as their 1st-born sibling.
  • Q: When should I refer a child for speech/language evaluation?
  • A: If the parents or physician have any concern for speech delay, then referral for evaluation is wise. Some speech-delayed children will eventually normalize and meet all milestones. It is difficult to distinguish who is constitutionally delayed from those who have another disorder. There are several indications for a prompt referral: no pointing or babbling by 1 year, no single words by 16 months, no 2-word spontaneous phrases by 2 years, no sentences by 3 years, poor intelligibility for age, child has behavioral "melt downs " ¯ or tantrums with efforts to communicate, or any regression in language skills.
  • Q: Do children raised in bilingual households have expressive language delay?
  • A: No. Living in a bilingual household is not a cause of expressive language delay. However, toddlers who are learning 2 languages may interchange words in both languages. Total vocabulary and phrase length are typically normal in these children by 2 " “3 years of age.
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