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Renal Injury, Emergency Medicine


Basics


Description


  • Kidneys are located in the retroperitoneal space and are surrounded by adipose tissue and loose areolar connective tissue.
  • Kidneys lie along the lower 2 thoracic vertebrae and 1st 4 lumbar vertebrae.
  • Left kidney is positioned slightly higher than the right.
  • Kidneys are not fixed:
    • Shift with the diaphragm and are supported by the renal arteries, veins, and adipose tissue to the renal (Gerota) fascia

Etiology


  • Most common of all urologic injuries
  • Occurs in ’ ˆ Ό8 " “10% of all abdominal trauma
  • Blunt renal trauma accounts for 80 " “85% of all renal injuries and is 5 times more common than penetrating injury:
    • Mechanisms include motor vehicle accidents, falls, domestic violence, and contact sports.
    • Pathophysiology includes rapid deceleration and displacement mechanisms.
    • ’ ˆ Ό20% of cases are associated with intraperitoneal injury.
  • Mechanisms responsible for significant renal injury almost never affect the kidney alone:
    • Most often disrupt and injure other vital organs that can be responsible for patient mortality
  • Renal injuries are graded by type and severity of injury (Association for the Surgery of Trauma [AAST] criteria)
    • Grade I
      • Contusion: Microscopic or gross hematuria, urologic studies normal
      • Hematoma: Subcapsular, nonexpanding without parenchymal laceration
    • Grade II:
      • Hematoma: Nonexpanding, perirenal hematoma confined to retroperitoneum
      • Laceration: <1 cm parenchymal depth of renal cortex without urinary extravasation
    • Grade III
      • Laceration: >1 cm parenchymal depth of renal cortex without collecting system rupture or urinary extravasation
    • Grade IV:
      • Laceration: Parenchymal laceration extending through renal cortex, medulla, and collecting system
      • Vascular: Main renal artery or vein injury with contained hemorrhage
    • Grade V:
      • Laceration: Completely shattered kidney
      • Vascular: Avulsion of renal hilum, devascularizing the kidney

  • The kidney is the organ most commonly damaged by blunt abdominal trauma.
  • Contributing factors:
    • Relatively larger size of kidneys compared with adults
    • 10th and 11th ribs are not completely ossified until the 3rd decade of life.
  • Significant abdominal injury occurs in about 5% of nonaccidental trauma cases but is the 2nd most common cause of death after head injury.

Diagnosis


Signs and Symptoms


History
  • Mechanism of injury and kinematics are important factors.
  • Majority of renal injuries are associated with injury of other abdominal organs.
  • In blunt trauma, note the type and direction (horizontal or vertical) of any deceleration or compressive forces.
  • In penetrating trauma, note the characteristic of the weapon (type and caliber), distance from the weapon, or the type and length of knife or impaling object:
    • Injuries result from a combination of kinetic energy and shear forces of penetrating object.

Physical Exam
  • Hematuria is the best indicator of traumatic urinary system injury:
    • Severity of renal trauma does not correlate with the degree of hematuria.
    • Absence of hematuria does not exclude renal injury
  • Microscopic hematuria with a systolic BP <90 mm Hg
  • Flank mass or ecchymosis
  • Tenderness in the flank, abdomen, or back
  • Fracture of the inferior ribs or spinal transverse processes
  • Nausea and vomiting

Essential Workup


  • In 1989, Mee et al. published the hallmark article (10-yr prospective study) that established guidelines for the evaluation and treatment of blunt renal trauma:
    • Major renal lacerations represent significant reparable renal injuries.
    • Adult patients at risk for having sustained major lacerations:
      • Gross hematuria, or
      • Microhematuria ( ≥3 " “5 RBCs/HPF) with shock (systolic BP ≤90 mm Hg) in the field or on arrival in the ED, or
      • History of sudden deceleration without hematuria or shock
  • IV contrast-enhanced CT scan is the procedure of choice in identifying urologic injury.
  • Guidelines are not applicable in cases of penetrating renal trauma or in children.
  • Adults with blunt renal trauma and gross hematuria, or microhematuria in the presence of shock, require renal imaging for further evaluation of renal injury.
  • In adults with penetrating renal trauma, significant injuries to the kidney and ureter can occur without hematuria:
    • Location of penetrating wound in relation to urinary tract is the most important factor in deciding need for radiographic imaging.
    • Penetrating injuries with any degree of hematuria should be imaged.
  • Important to rule out coexisting injuries

Diagnosis Tests & Interpretation


Lab
  • Urinalysis: Gross hematuria or >50 RBCs/HPF in adults and >20 RBC/HPF in children is suggestive of renal injury.
  • Baseline lab values including hematocrit and BUN/creatinine should be obtained.

Imaging
  • Plain abdominal films:
    • May show fractured inferior ribs or transverse processes, a unilateral enlarged kidney shadow, or obscuring of the psoas margin
  • IV pyelogram (IVP):
    • Bolus infusion IVP with nephrotomography study of choice in institutions without 24-hr availability of CT
    • Rapid injection of 1.5 " “2 mL of contrast material per kilogram of body weight to a maximum or 150 mL after obtaining a preliminary kidney, ureter, and bladder image
    • Postinfusion supine film is obtained followed by 1-, 2-, and 3-min supine films.
      • Allows evaluation for renal viability and function
      • Extravasation reflects injury to the collecting system.
      • Nonvisualization of a kidney may indicate renal pedicle injury or parenchymal shattering.
      • Abnormal findings are often nonspecific and require more definitive studies.
  • Ultrasound:
    • Role in evaluation of renal injury is controversial
    • Routinely performed at bedside in trauma patients as part of focused assessment with sonography in trauma (FAST)
    • May show size of perirenal hematoma and whether it is expanding or resolving
    • Low sensitivity for identification of retroperitoneal free fluid
    • Otherwise, exam is nonspecific and does not provide enough information
  • CT scan:
    • An IV contrast-enhanced helical CT scan is the diagnostic procedure of choice.
    • Superior anatomic detail and diagnostic accuracy of 98% for renal injury
    • Sensitive indicator of minor extravasation, parenchymal laceration, vascular injury, and nonrenal injuries

  • Major blunt renal trauma can occur in the absence of gross hematuria or shock (as children have a high catecholamine output after trauma, which maintains BP until ’ ˆ Ό50% of blood volume has been lost).
  • Meta-analysis has defined 50 RBC/HPF as the microscopic quantity below which imaging can be omitted and no significant injuries missed.
  • CT scan is the imaging modality of choice.

Diagnostic Procedures/Surgery
  • Renal parenchymal injury
  • Renal vascular injury
  • Ureteral injury
  • Bladder or urethral injury

Treatment


Pre-Hospital


  • Obtain details of injury from pre-hospital providers.
  • IV access
  • Penetrating wounds or evisceration should be covered with sterile dressings.

Initial Stabilization/Therapy


  • Airway management (including C-spine immobilization)
  • Standard Advanced Trauma Life Support (ATLS) resuscitation measures:
    • Adequate IV access, including central lines and cutdowns, as dictated by the patients hemodynamic status
    • Fluid resuscitation, initially with 2 L of crystalloid (NS or lactated Ringer solution), followed by blood products as needed
  • Rule out potential life-threatening injuries 1st.

Ed Treatment/Procedures


  • Immediate laparotomy in the acutely injured patient who is hemodynamically unstable with presumed hemoperitoneum and renal injury
  • Significant injuries (grades II " “V) are found in only 5.4% of renal trauma cases.
  • 98% of blunt renal injuries can be managed nonoperatively.
  • ’ ˆ Ό80 " “90% of renal injuries have major associated organ injury that can affect the choice of renal injury management.
  • Angiography and selective renal embolization has an increasing role and is an alternative treatment to laparotomy in patients not requiring immediate surgery.
  • Penetrating renal trauma:
    • Previously exploratory laparotomy was recommended for all patients with penetrating renal injuries.
    • Nonoperative management has become more accepted for grades I " “III with penetrating renal injuries in the absence of associated intra-abdominal injury or hemodynamic instability
  • Blunt renal trauma:
    • Isolated renal injury without significant associated injuries occurs more commonly from blunt trauma, and in most circumstances, can be managed nonoperatively.
    • Classes I and II: Contusions and minor lacerations with stable vital signs and urographically normal renal function can be managed nonoperatively.
    • Class III: Renal lacerations with urinary extravasation:
      • Controversy between operative vs. nonoperative management
      • Management should be based on degree of injury using CT scanning.
    • Classes IV and V: Shattered kidney or renal pedicle injuries and hemodynamically unstable patients require emergent laparotomy.
    • All ureteral injuries require operative repair.

Follow-Up


Disposition


Admission Criteria
Patients with significant renal injury require hospitalization for definitive laparotomy or observation. ‚  
Discharge Criteria
  • Adult trauma patients without hematuria, shock, or no renal injury confirmed radiographically
  • Adult blunt trauma patient with microhematuria ( ≥3 " “5 RBCs/HPF) but no shock (systolic BP ≤90 mm Hg)
  • Pediatric blunt trauma patient with ≤50 RBC/HPF and no other coexisting major organ injuries

Issues for Referral
  • Outpatient referral to urologist should be made for microhematuria to ensure that it does not represent a more serious underlying condition.
  • Urinoma formation is the most common complication (1 " “7%) of patients with renal trauma:
    • Urinary extravasation resolves spontaneously in 76 " “87% of cases

Additional Reading


  • Broghammer ‚  JA, Fisher ‚  MB, Santucci ‚  RA. Conservative management of renal trauma: A review. Urology.  2007;70(4):623 " “629.
  • Mee ‚  SL, McAninch ‚  JW, Robinson ‚  AL, et al. Radiographic assessment of renal trauma: A 10-year prospective study of patient selection. J Urol.  1989;141:1095 " “1098.
  • Santucci ‚  RA, Wessells ‚  H, Bartsch ‚  G, et al. Evaluation and management of renal injuries: Consensus statement of the renal trauma subcommittee. BJU Int.  2004;93(7):937 " “954.
  • Shoobridge ‚  JJ, Corcoran ‚  NM, Martin ‚  KA, et al. Contemporary management of renal trauma. Rev Urol.  2011;13(2):65 " “72.
  • Tinkoff ‚  G, Esposito ‚  TJ, Reed ‚  J, et al. American Association for the Surgery of Trauma Organ Injury Scale I: Spleen, liver, and kidney, validation based on the National Trauma Data Bank. J Am Coll Surg.  2008;207(5):646 " “655.

Codes


ICD9


  • 866.00 Injury to kidney without mention of open wound into cavity, unspecified injury
  • 866.01 Injury to kidney without mention of open wound into cavity, hematoma without rupture of capsule
  • 866.02 Injury to kidney without mention of open wound into cavity, laceration
  • 866.03 Injury to kidney without mention of open wound into cavity, complete disruption of kidney parenchyma
  • 866.0 Injury to kidney without mention of open wound into cavity
  • 866.10 Injury to kidney with open wound into cavity, unspecified injury
  • 866.11 Injury to kidney with open wound into cavity, hematoma without rupture of capsule
  • 866.12 Injury to kidney with open wound into cavity, laceration
  • 866.13 Injury to kidney with open wound into cavity, complete disruption of kidney parenchyma
  • 866.1 Injury to kidney with open wound into cavity

ICD10


  • S37.009A Unspecified injury of unspecified kidney, initial encounter
  • S37.019A Minor contusion of unspecified kidney, initial encounter
  • S37.049A Minor laceration of unspecified kidney, initial encounter
  • S37.069A Major laceration of unspecified kidney, initial encounter
  • S37.001A Unspecified injury of right kidney, initial encounter
  • S37.002A Unspecified injury of left kidney, initial encounter
  • S37.011A Minor contusion of right kidney, initial encounter
  • S37.012A Minor contusion of left kidney, initial encounter
  • S37.021A Major contusion of right kidney, initial encounter
  • S37.022A Major contusion of left kidney, initial encounter
  • S37.029A Major contusion of unspecified kidney, initial encounter
  • S37.031A Laceration of right kidney, unspecified degree, init encntr
  • S37.039A Laceration of unsp kidney, unspecified degree, init encntr
  • S37.041A Minor laceration of right kidney, initial encounter
  • S37.042A Minor laceration of left kidney, initial encounter
  • S37.051A Moderate laceration of right kidney, initial encounter
  • S37.052A Moderate laceration of left kidney, initial encounter
  • S37.059A Moderate laceration of unspecified kidney, initial encounter
  • S37.061A Major laceration of right kidney, initial encounter
  • S37.062A Major laceration of left kidney, initial encounter
  • S37.091A Other injury of right kidney, initial encounter
  • S37.092A Other injury of left kidney, initial encounter
  • S37.099A Other injury of unspecified kidney, initial encounter

SNOMED


  • 40095003 injury of kidney (disorder)
  • 70092007 Contusion of kidney (disorder)
  • 262893009 Laceration of kidney (disorder)
  • 283905005 Avulsion of kidney (disorder)
  • 20341008 Injury of kidney without open wound into abdominal cavity (disorder)
  • 210197003 Closed injury of kidney (disorder)
  • 210811000 Renal blood vessel injury (disorder)
  • 61474001 Injury of kidney with open wound into abdominal cavity (disorder)
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