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Pilonidal Disease


BASICS


DESCRIPTION


  • Pilonidal disease results from an abscess, or sinus tract, in the upper part of the natal (gluteal) cleft.
  • Synonym(s): jeep disease

EPIDEMIOLOGY


Incidence
  • 16 to 26/100,000 per year
  • Predominant sex: male > female (3 to 4:1)
  • Predominant age: 2nd to 3rd decades, rare >45 years
  • Ethnic consideration: whites > blacks > Asians

Prevalence
Surgical procedures show male:female ratio of 4:1, yet incidence data are 10:1. ‚  

ETIOLOGY AND PATHOPHYSIOLOGY


Pilonidal means "nest of hair " ; hair in the natal cleft allows hair to be drawn into the deeper tissues via negative pressure caused by movement of the buttocks (50%); follicular occlusion from stretching, and blocking of pores with debris (50%). ‚  
  • Inflammation of SC gluteal tissues with secondary infection and sinus tract formation
  • Polymicrobial, likely from enteric pathogens given proximity to anorectal contamination

Genetics
  • Congenital dimple in the natal cleft/spina bifida occulta
  • Follicular-occluding tetrad: acne conglobata, dissecting cellulitis, hidradenitis suppurativa, pilonidal

RISK FACTORS


  • Sedentary/prolonged sitting
  • Excessive body hair
  • Obesity/increased sacrococcygeal fold thickness
  • Congenital natal dimple
  • Trauma to coccyx

GENERAL PREVENTION


  • Weight loss
  • Trim hair in/around gluteal cleft weekly
  • Hygiene
  • Ingrown hair prevention/follicle unblocking

DIAGNOSIS


HISTORY


Three distinct clinical presentations ‚  
  • Asymptomatic: painless cyst or sinus at the top of the gluteal cleft
  • Acute abscess: severe pain, swelling, discharge from the top of the gluteal cleft that may or may not have drained spontaneously
  • Chronic abscess: persistent drainage from a sinus tract at the top of the gluteal cleft

PHYSICAL EXAM


  • Common: inflamed cystic mass at the top of the gluteal cleft with limited surrounding erythema ‚ ± drainage or a sinus tract
  • Less common: significant cellulitis of the surrounding tissues near the gluteal cleft

DIFFERENTIAL DIAGNOSIS


  • Furunculosis
  • Hidradenitis suppurativa
  • Anal fistula
  • Perirectal abscess
  • Crohn disease

DIAGNOSTIC TESTS & INTERPRETATION


Initial Tests (lab, imaging)
  • Consider CBC and wound culture but generally not necessary for less-severe infections.
  • MRI might be considered to differentiate between perirectal abscess and pilonidal disease.

TREATMENT


GENERAL MEASURES


Shave area; remove hair from crypts weekly. ‚  

MEDICATION


  • Antibiotics not indicated unless there is significant cellulitis (1).
  • If antibiotics are needed, a culture to direct therapy might be useful.
  • Cefazolin plus metronidazole or amoxicillin-clavulanate are often used empirically if cellulitis is suspected.

ISSUES FOR REFERRAL


  • Patients who cannot comply with frequent dressing changes required after incision and drainage (I&D)
  • Patients who have recurrence after I&D
  • Patients who have complex disease with multiple sinus tracts

ADDITIONAL THERAPIES


  • I&D with only enough packing to allow the cyst to drain; overpacking not indicated
  • Antibiotics only if significant cellulitis; temporizing, not curative
  • Negative pressure wound therapy (2)[A]
  • Laser epilation of hair in the gluteal fold (3,4)[B]

SURGERY/OTHER PROCEDURES


Six levels of care based on severity or recurrence of disease; recent innovations in technique are aimed at expediting healing and minimizing recurrence ‚  
  • I&D, remove hair, curette granulation tissue (5,6)[A].
  • Excision of midline "pits "  allows drainage of lateral sinus tracts (pit picking) (7,8)[A].
  • Pilonidal cystotomy: Insert probe into sinus tract, excise overlying skin, and close wound (7,9)[B].
  • Marsupialization: Excise overlying skin and roof of cyst, and suture skin edges to cyst floor (5,10)[B].
  • Excision: use of flap closure. No clear benefit for open healing over surgical closure (11)[B]
  • Off-midline surgical excision (cleft lift or modified Karydakis procedure): A systematic review showed a clear benefit in favor of off-midline rather than midline wound closure. When closure of pilonidal sinuses is the desired surgical option, off-midline closure should be the standard management (5,7,12)[A].

INPATIENT CONSIDERATIONS


Admission Criteria/Initial Stabilization
  • Severe cellulitis
  • Large area excision

ONGOING CARE


FOLLOW-UP RECOMMENDATIONS


  • Frequent dressing changes required after I&D
  • Follow-up wound checks to assess for recurrence.

Patient Monitoring
Monitor for fever, more extensive cellulitis. ‚  

PATIENT EDUCATION


  • Wash area briskly with washcloth daily.
  • Shave the area weekly.
  • Remove any embedded hair from the crypt.
  • Avoid prolonged sitting.

PROGNOSIS


  • Simple I&D has a 55% failure rate; median time to healing is 5 weeks.
  • More extensive surgical excisions involve hospital stays and longer time to heal.

COMPLICATIONS


Malignant degeneration is a rare complication of untreated chronic pilonidal disease. ‚  

REFERENCES


11 Mavros ‚  MN, Mitsikostas ‚  PK, Alexiou ‚  VG, et al. Antimicrobials as an adjunct to pilonidal disease surgery: a systematic review of the literature. Eur J Clin Microbiol Infect Dis.  2013;32(7):851 " “858.22 Farrell ‚  D, Murphy ‚  S. Negative pressure wound therapy for recurrent pilonidal disease: a review of the literature. J Wound Ostomy Continence Nurs.  2011;38(4):373 " “378.33 Loganathan ‚  A, Arsalani Zadeh ‚  R, Hartley ‚  J. Pilonidal disease: time to reevaluate a common pain in the rear! Dis Colon Rectum.  2012;55(4):491 " “493.44 Oram ‚  Y, Kahraman ‚  F, Karincao „ Ÿlu ‚  Y, et al. Evaluation of 60 patients with pilonidal sinus treated with laser epilation after surgery. Dermatol Surg.  2010;36(1):88 " “91.55 Humphries ‚  AE, Duncan ‚  JE. Evaluation and management of pilonidal disease. Surg Clin North Am.  2010;90(1):113 " “124, Table of Contents.66 Kement ‚  M, Oncel ‚  M, Kurt ‚  N, et al. Sinus excision for the treatment of limited chronic pilonidal disease: results after a medium-term follow-up. Dis Colon Rectum.  2006;49(11):1758 " “1762.77 Al-Khamis ‚  A, McCallum ‚  I, King ‚  PM, et al. Healing by primary versus secondary intention after surgical treatment for pilonidal sinus. Cochrane Database Syst Rev.  2010;(1):CD006213.88 Iesalnieks ‚  I, Deimel ‚  S, Kienle ‚  K, et al. Pit-picking surgery for pilonidal disease [in German]. Chirurg.  2011;82(10):927 " “931.99 da Silva ‚  JH. Pilonidal cyst: cause and treatment. Dis Colon Rectum.  2000;43(8):1146 " “1156.1010 Aydede ‚  H, Erhan ‚  Y, Sakarya ‚  A, et al. Comparison of three methods in surgical treatment of pilonidal disease. ANZ J Surg.  2001;71(6):362 " “364.1111 Washer ‚  JD, Smith ‚  DE, Carman ‚  ME, et al. Gluteal fascial advancement: an innovative, effective method for treating pilonidal disease. Am Surg.  2010;76(2):154 " “156.1212 Ates ‚  M, Dirican ‚  A, Sarac ‚  M, et al. Short and long-term results of the Karydakis flap versus the Limberg flap for treating pilonidal sinus disease: a prospective randomized study. Am J Surg.  2011;202(5):568 " “573.

ADDITIONAL READING


  • Aygen ‚  E, Arslan ‚  K, Dogru ‚  O, et al. Crystallized phenol in nonoperative treatment of previously operated, recurrent pilonidal disease. Dis Colon Rectum.  2010;53(6):932 " “935.
  • Bradley ‚  L. Pilonidal sinus disease: a review. Part one. J Wound Care.  2010;19(11):504 " “508.
  • Harlak ‚  A , Mentes ‚  O, Kilic ‚  S , et al. Sacrococcygeal pilonidal disease: analysis of previously proposed risk factors. Clinics (Sao Paulo).  2010;65(2):125 " “131.
  • Rao ‚  MM, Zawislak ‚  W, Kennedy ‚  R, et al. A prospective randomised study comparing two treatment modalities for chronic pilonidal sinus with a 5-year follow-up. Int J Colorectal Dis.  2010;25(3):395 " “400.
  • Theodoropoulos ‚  GE , Vlahos ‚  K , Lazaris ‚  AC , et al. Modified Bascom 's asymmetric midgluteal cleft closure technique for recurrent pilonidal disease: early experience in a military hospital. Dis Colon Rectum.  2003;46(9):1286 " “1291.

CODES


ICD10


  • L05.91 Pilonidal cyst without abscess
  • L05.92 Pilonidal sinus without abscess
  • L05.01 Pilonidal cyst with abscess
  • L05.02 Pilonidal sinus with abscess

ICD9


  • 685.1 Pilonidal cyst without mention of abscess
  • 685.0 Pilonidal cyst with abscess

SNOMED


  • 432863009 pilonidal disease (disorder)
  • 47639008 cyst - pilonidal (disorder)
  • 85224001 pilonidal cyst with abscess (disorder)
  • 311453002 Pilonidal sinus of natal cleft
  • 76545008 pilonidal cyst without abscess (disorder)
  • 200715006 Pilonidal sinus without abscess
  • 431709001 Pilonidal abscess of natal cleft

CLINICAL PEARLS


  • Avoid prolonged sitting.
  • Lose weight.
  • Trim hair in gluteal cleft weekly.
  • Refer recurring infections for more definitive surgical management.
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