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Perirectal Abscess, Emergency Medicine


Basics


Description


Localized infection and accumulation of purulent material adjacent to anus or rectum ‚  

Etiology


  • Anal crypt gland infection, with spread to adjacent areas separated by muscle and fascia:
    • Perianal:
      • Most common
      • Usually with red bulge near anus
    • Ischiorectal:
      • Large potential space
      • May become very large before diagnosed
      • Can communicate posteriorly with other side forming "horseshoe "  abscess
    • Intersphincteric:
      • Contained at primary site of origin between internal and external sphincters
    • Supralevator:
      • Very deep above levator ani
      • Needs operative debridement under general anesthesia
      • Often systemic symptoms before diagnosis is made
  • Bacterial cause is typically a mix of stool pathogens:
  • Associated diseases:
    • Diabetes
    • Inflammatory bowel disease
    • Malignancy
    • Immunocompromised host

Diagnosis


Signs and Symptoms


  • Pain: Perianal, rectal, or pelvic
  • Swelling, fluctuance, drainage, fever

History
  • Perianal pain:
    • Aggravated by defecation, sitting, coughing
  • Dull deep pelvic or rectal pain:
    • Less pain if arises above dentate line (ischiorectal and supralevator)
  • Rectal or perirectal drainage
  • Fever/chills
  • Constipation

Physical Exam
  • Perianal swelling, erythema, induration, fluctuance, tenderness
  • Inner cleft buttock abscess = red flag
    • Rectal abscess can track out to buttock
  • Rectal exam is the most important diagnostic intervention
    • Rectal swelling or tenderness
    • Fistula can be probed, or palpated as a cord

Essential Workup


  • Careful history and physical exam with rectal exam are paramount in making diagnosis.
  • Have high index of suspicion for any constant perirectal pain.

Diagnosis Tests & Interpretation


No labs or imaging routinely indicated ‚  
Lab
  • CBC: Leukocytosis with left shift
  • Wound culture: Not typically indicated
  • Blood cultures: Mainly for sepsis

Imaging
  • CT (with IV contrast, +/ " “ PO contrast)
  • MRI (helpful with detecting fistulas)
  • Endoanal US sometimes used

Diagnostic Procedures/Surgery
Incision and drainage (I&D) is the definitive management. ‚  

Differential Diagnosis


  • Anal fissure
  • Sentinel pile in the posterior midline or anterior midline
  • Thrombosed or inflamed hemorrhoids
  • Anal ulcer (i.e., HIV)
  • Proctitis (i.e., gonococcal)
  • Anorectal carcinoma

Treatment


Initial Stabilization/Therapy


Pain medication ‚  

Ed Treatment/Procedures


  • Delayed drainage may worsen outcome
  • Bedside drainage:
    • Only if localized perianal abscess
      • Probe to rule out deeper tract
    • Radial incision close to anal verge
    • Explore cavity, breaking any loculations.
    • Irrigate liberally.
    • Loose packing removed at 48 hr.
  • Operative debridement under general anesthesia:
    • If local anesthesia is inadequate, or deeper abscess
  • Antibiotics rarely necessary:
    • Extensive cellulitis
    • Immunosuppression
    • Valvular heart disease
    • Systemic infection
    • Prosthetic device
    • PO:
      • Amoxicillin clavulanate or fluoroquinolone
      • Consider MRSA coverage
    • IV:
      • Cefoxitin
      • Ampicillin sulbactam
      • Combination therapy with ampicillin, gentamicin, and clindamycin or metronidazole
  • Postoperative care:
    • Sitz baths TID 24 hr after I&D
    • High-fiber diet or bulking agent
    • Analgesic

Medication


  • Amoxicillin clavulanate: 875 mg PO q12h or 500 mg PO q8h
  • Ampicillin sulbactam: 1.5 " “3 g IV q6h
  • Cefoxitin: 1 " “2 g IV q6 " “8h
  • Clindamycin: 600 " “900 mg IV div. q8h
  • Gentamicin: 3 " “6 mg/kg/d IV div. q8h
  • Metronidazole: 7.5 mg/kg IV q6h

Follow-Up


Disposition


Admission Criteria
  • Need for operative drainage
  • Systemic toxicity/signs of sepsis

Discharge Criteria
Adequate I&D with complete drainage ‚  
Issues for Referral
All should be referred to surgeon in 24 " “48 hr ‚  

Followup Recommendations


Surgeon referral within 24 " “48 hr to evaluate for fistula: ‚  
  • Fistulas develop in 25 " “50% of anorectal abscesses.

Pearls and Pitfalls


  • Be certain of extent of abscess:
    • Thorough rectal exam and probing is mandatory.
    • Imaging adds insight into deeper areas not accessible to exam
  • Deeper abscesses above dentate line have less pain and can present with isolated fever

Additional Reading


  • Marcus ‚  RH, Stine ‚  RJ, Cohen, ‚  MA. Perirectal abscess. Ann Emerg Med.  1995;25(5):597 " “603.
  • Rizzo ‚  JA, Naig ‚  AL, Johnson ‚  EK. Anorectal abscess and fistula-in-ano: Evidence-based management. Surg Clin North Am.  2010;90(1):45 " “68.
  • Schubert ‚  MC, Sridhar ‚  S, Schade ‚  RR, et al. What every gastroenterologist needs to know about common anorectal disorders. World J Gastroenterol.  2009;15:3201 " “3209.
  • Steele ‚  SR, Kumar ‚  R, Feingold ‚  DL, et al. Practice parameters for the treatment of perianal abscess and fistula-in-ano. Dis Colon Rectum.  2011;54:1465 " “1474.

See Also (Topic, Algorithm, Electronic Media Element)


  • Abscess
  • Anal Fissure
  • Hemorrhoid

Codes


ICD9


  • 565.1 Anal fistula
  • 566 Abscess of anal and rectal regions

ICD10


  • K61.0 Anal abscess
  • K61.1 Rectal abscess
  • K61.3 Ischiorectal abscess
  • K60.4 Rectal fistula

SNOMED


  • 91669008 Perirectal abscess (disorder)
  • 36046008 Ischiorectal abscess (disorder)
  • 82127005 perianal abscess (disorder)
  • 235795007 Intersphincteric abscess (disorder)
  • 197163002 Supralevator abscess (disorder)
  • 286977005 Ischiorectal abscess/fistula (disorder)
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