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Munchausen Syndrome, Emergency Medicine


Basics


Description


  • A neurotic disorder in which the patient fakes signs or symptoms without tangible personal benefit other than to experience the sick role.
  • Most dramatic form of chronic factitious disorder with a predominance of physical findings.
  • The nature of the disorder resists rigorous study but possible risk factors include:
    • Males
    • Less severe factitious disorders are more common in women
    • Unmarried
    • Age in the forties
    • Personality disorder
    • A history of sadistic and rejecting parents
    • A history of chronic childhood illness

Etiology


  • Factitious disorder:
    • 3 DSM-IV diagnostic criteria:
      • Intentional production of physical or psychological signs
      • Motivation to assume the sick role
      • Absence of external incentives
      • Predominance of symptoms rather than physical findings
  • Classic Munchausen syndrome:
    • Most severe and chronic form of factitious disorders
    • Predominantly physical findings
  • Clinical clusters:
    • Self-induced infection
    • Simulated specific illnesses with no actual disorder
    • Chronic wounds
    • Self-medication

  • Munchausen by proxy:
    • The patients illness is caused by the caregiver, not the patient
    • The motivation for the caregiver's behavior is to assume the sick role by proxy
    • The caregiver inflicts injury or induces illness in their charge, usually a child
    • Commonly parents (mostly mothers)
  • May simulate injury and disease in a number of ways:
    • Inflicts injury
    • Induces Illness
    • Fabricates symptoms
    • Exaggerates symptoms of the child's illness causing overaggressive medical interventions
  • The perpetrator usually refuses to acknowledge the deception
  • Cessation of the symptoms when the patient and caregiver are separated

Caregivers of elderly patients may also be perpetrators in Munchausen by proxy ‚  

Diagnosis


Signs and Symptoms


History
  • Inappropriate or bizarre use of the ED
  • Frequent visits
  • Numerous hospital admissions
  • Peregrination: Travel from hospital to hospital
  • Pseudologia fantastica:
    • Intricate and colorful stories associated with the presentation
  • Alteration of biographical information:
    • Use of aliases
    • Change date of birth by 1 digit
  • Escalating demands for diagnostic testing and therapeutic interventions
  • Hostility toward the health care providers when questioned
  • Evasiveness regarding details of the presenting complaint
  • The patient provides excessive medical documentation
  • Masochistic acceptance of painful procedures
  • The patient appears more comfortable than is likely considering the disease
  • The patient demonstrates unusually strong medical knowledge
  • Frequent homelessness and significant wandering between cities and states
  • An absence of close interpersonal relationships
  • Self-medication
  • Abdominal complaints with history of repeated negative laparotomies (laparotomaphilia migrans)
  • Witnessed intentional acts to fake illness:
    • Inappropriate ingestion of medication to reproduce physical findings
    • Injection of contaminants (feces, bacteria, sputum, corrosives)
    • Self-induced wounds
    • Swallowing blood to simulate a GI hemorrhage
    • Self-phlebotomy
    • Instrument tampering

Physical Exam
  • Fever:
    • Factious from manipulation of thermometer
    • Induced from injection of contaminants
  • Self-induced wounds
  • Chronic wounds
  • Multiple scars
  • Foreign bodies in wounds, ear canals, urethra

Essential Workup


  • Diligent detective work is needed:
    • Retrieval of records from other hospitals
    • Call on family members to discuss past history for inconsistencies and excessive use
    • Call personal physician for background and to coordinate information
    • Search patients room and belongings to establish the method of deception
  • Conclusive proof of faking disease is needed to make the diagnosis

Diagnosis Tests & Interpretation


Lab
  • Direct observation of the patient when obtaining tests to prevent faking results
  • Commonly faked lab results:
    • Hemoccult positive stool
    • Hematuria (intentionally dripping blood into urine sample)
    • Hypoglycemia (self-administration of insulin)
  • Abnormal results from self-medication:
    • Low hematocrit (ingestion of warfarin or self-phlebotomy)
    • Elevated INR (ingestion of warfarin)
    • Thyroid function tests (ingestion of thyroxine)
    • Low serum glucose (injection of insulin or ingestion of sulfonylurea)
  • Evidence of intent to fake illness:
    • Testing stool for phenolphthalein may detect laxative abuse
    • Serum C-peptide with high insulin levels:
      • Low C-peptide: Exogenous administration of insulin
      • Elevated C-peptide: Endogenous hypoglycemia or sulfonylurea ingestion

Imaging
Do not rely on imaging brought by the patient ‚  
Diagnostic Procedures/Surgery
Avoid unless clear objective findings indicate the necessity of a procedure ‚  

Differential Diagnosis


  • True illness:
    • Primary illness unrelated to a psychiatric disorder
  • Secondary to a comorbid condition associated with factitious disorders:
    • Secondary to self-destructive acts in patients with dementia, psychotic disorders, or mental retardation
    • Secondary to diagnostic and therapeutic procedures
  • Malingering:
    • Clear-cut secondary gain
  • Conversion disorder:
    • Deficits of the voluntary motor or sensory neurologic system that are not consciously produced
  • Somatization disorder (hysteria, Briquet syndrome):
    • Symptoms that involve multiple organs, that varies over time, and are not consciously produced
  • Other neurotic disorders:
    • Anxiety
    • Depression

Treatment


Initial Stabilization/Therapy


Treatment should be limited to stabilization of life or limb threats caused by acts of self-harm ‚  

Ed Treatment/Procedures


  • Identify objective physical illness and treat as appropriate
  • Document history and findings suggestive of factitious illness
  • List of all the aliases, addresses, and date of births that the patient is known to use
  • Summarize the patients known modus operandi (the factitious histories and behaviors that he or she has presented with)
  • Ensure that the information will be communicated or available to all doctors who are likely to come into contact with the patient
  • Confrontation of the patient in the ED is controversial and should only occur when unambiguous evidence is gathered
  • Report Munchausen syndrome by proxy to child protective services

Follow-Up


Disposition


Admission Criteria
  • Injuries and disease caused by self-harm
  • Munchausen by proxy:
    • When the diagnosis is suspected but there is not enough evidence to have child protective services take custody
  • Observation to collect evidence of faking disease:
    • May also allow setting to rule out rare organic etiologies
  • To establish a long-term plan to prevent future self-harm and iatrogenic adverse events
  • Psychiatric admission may be of benefit, but it is rarely accepted by the patient

Discharge Criteria
  • Medical stability
  • Not an active threat to harm self
  • Appropriate referral for medical and psychiatric follow-up arranged

Issues for Referral
  • May offer psychiatric referral as a method of dealing with stress caused by illness
  • Psychiatric providers located directly in medical settings (e.g., primary care physician office) may be more accepted. Overall, this is a chronic illness with poor prognosis

Followup Recommendations


Maintain contact between the patient and an identified provider for that patient. ‚  

Additional Reading


  • Kenedi ‚  CA, Shirey ‚  KG, Hoffa ‚  M, et al. Laboratory diagnosis of factitious disorder: A systematic review of tools useful in the diagnosis of Munchausens syndrome. N Z Med J.  2011;124:66 " “81.
  • Mehta ‚  NJ, Khan ‚  IA. Cardiac Munchausen syndrome. Chest.  2002;122(5):1649 " “1653.
  • Robertson ‚  MM, Cervilla ‚  JA. Munchausen's syndrome. Br J Hosp Med.  1997;58(7):308 " “312.
  • Souid ‚  AK, Keith ‚  DV, Cunningham ‚  AS. Munchausen syndrome by proxy. Clin Pediatr (Phila).  1998;37(8):497 " “503.
  • Steel ‚  RM. Factitious disorder (Munchausen's syndrome). J R Coll Physicians Edinb.  2009;39:343 " “347.
  • Stern ‚  TA. Munchausen's syndrome revisited. Psychosomatics.  1980;21:329 " “336.
  • Walker ‚  EA. Dealing with patients who have medically unexplained symptoms. Semin Clin Neuropsychiatry.  2002;7:187 " “195.

See Also (Topic, Algorithm, Electronic Media Element)


Abuse, Pediatric ‚  

Codes


ICD9


301.51 Chronic factitious illness with physical symptoms ‚  

ICD10


  • F68.11 Factitious disorder w predom psych signs and symptoms
  • F68.12 Factitious disorder w predom physical signs and symptoms
  • F68.13 Factitious disord w comb psych and physcl signs and symptoms
  • F68.10 Factitious disorder, unspecified
  • F68.1 Factitious disorder

SNOMED


  • 21586000 Munchausens syndrome
  • 95637005 Munchausen's by proxy
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