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Huntington Disease


The Basics


Written by the doctors and editors at UpToDate � �
What is Huntington disease? " � Huntington disease is a disorder that causes people to move in odds ways and that can affect their mood and the way they think. In people with Huntington disease, nerve cells in a part of the brain die. The disease is passed on in families. If your mother or father has Huntington disease, you have a 50-50 chance of having it, too. � �
People with Huntington disease usually start to show symptoms between the ages of 40 and 60. Some people show symptoms much earlier. � �
What are the symptoms of Huntington disease? " � The symptoms can include: � �
  • Movements (called "chorea " �) that you cant control in the face, trunk, arms, or legs
  • Feeling depressed, anxious, irritable, angry, or like you don't care about anything
  • Trouble interacting with other people
  • Seeing or believing in things that are not there (called hallucinations)
  • Trouble thinking clearly and forgetting things
  • Weight loss

At first, the symptoms might be very slight, but they slowly get worse over time. � �
People with Huntington disease are at risk of suicide. If you feel sad or depressed, talk to your doctor or nurse about it. There are often treatments that can help. � �
Is there a test for Huntington disease? " � Yes. There is a blood test to check for the gene that causes Huntington disease. Some people have this test before they show any symptoms. But if you are thinking of having this test, ask your doctor to send you to a genetic counselor before you have the test. A genetic counselor can help you learn about all the possible risks and benefits of having the test. For instance, a genetic counselor can help you find out: � �
  • What the chances are that your kids will have Huntington disease
  • How soon you might have symptoms, if the test shows you have the disease
  • Whether you could have problems with insurance if the test shows you have the disease

How is Huntington disease treated? " � There are no medicines that deal with all the symptoms of Huntington disease. But there are lots of treatments to help with specific symptoms. For instance, people who are depressed or anxious can take depression and anxiety medicines. Likewise, people who see things that are not real can take medicines to deal with that problem. � �
People with Huntington disease sometimes also use walkers, wheelchairs, or other devices that can help them manage their problems. Plus, they sometimes work with physical or speech therapists to learn special exercises that can help them manage. � �
Certain medicines can sometimes help with the sudden, uncontrolled movements caused by Huntington disease, called chorea. But these medicines can sometimes also have bothersome or severe side effects, so doctors tend to use them only as a last resort. Chorea can get worse with stress, anxiety, and depression, so treating these problems can help with chorea too. Padded furniture and beds can lower the chances of injury from chorea. � �
Unfortunately, there is no cure for Huntington disease. Most people die 10 to 30 years after the symptoms begin. If you have the disease, talk to your loved ones about the type of care you would like to have when you get really sick. That way they will know what to do, even if you become unable to speak for yourself. � �
What if I want to get pregnant? " � Talk to your doctor nurse before you start trying to get pregnant. If you are taking medicines, you might need to switch to different medicines that are safer for a baby. You also might want to talk to a genetic counselor about the chances that any children you might have would develop Huntington disease. � �
All topics are updated as new evidence becomes available and our peer review process is complete. � �
This topic retrieved from UpToDate on: Nov 04, 2014. � �
Topic 15820 Version 2.0 � �
Release: 22.8 - C22.208 � �
� � 2014 UpToDate, Inc. All rights reserved. � �

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This information is not specific medical advice and does not replace information you receive from your health care provider. This is only a brief summary of general information. It does NOT include all information about conditions, illnesses, injuries, tests, procedures, treatments, therapies, discharge instructions or life-style choices that may apply to you. You must talk with your health care provider for complete information about your health and treatment options. This information should not be used to decide whether or not to accept your health care providers advice, instructions or recommendations. Only your health care provider has the knowledge and training to provide advice that is right for you.The use of UpToDate content is governed by the UpToDate Terms of Use. � �2014 UpToDate, Inc. All rights reserved. � �

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