(ben ZOE na tate)
Cough: Symptomatic relief of cough
Hypersensitivity to benzonatate, related compounds, or any component of the formulation
Cough: Oral: 100 to 200 mg 3 times/day as needed for cough (maximum single dose: 200 mg; maximum dose: 600 mg/day)
Refer to adult dosing.
Cough: Children >10 years and Adolescents: Refer to adult dosing.
There are no dosage adjustments provided in the manufacturers labeling.
There are no dosage adjustments provided in the manufacturers labeling.
Oral: Swallow capsule whole (do not break, chew, dissolve, cut, or crush). If capsules are chewed or dissolved in the mouth, oral mucosa anesthesia may occur and could lead to choking. If numbness or tingling of the tongue, mouth, throat, or face occurs, refrain from oral ingestion of food or liquid until numbness has resolved.
Store at 25 ‚ °C (77 ‚ °F); excursions permitted between 15 ‚ °C to 30 ‚ °C (59 ‚ °F to 86 ‚ °F). Protect from light.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Capsule, Oral:
Tessalon: 200 mg [DSC] [contains fd&c yellow #10 (quinoline yellow), methylparaben, propylparaben]
Tessalon Perles: 100 mg
Zonatuss: 150 mg [DSC] [contains brilliant blue fcf (fd&c blue #1)]
Generic: 100 mg, 150 mg, 200 mg
There are no known significant interactions.
Frequency not defined.
Cardiovascular: Chest numbness
Central nervous system: Chills, confusion, dizziness, hallucination, headache, sedation
Dermatologic: Pruritus, skin rash
Gastrointestinal: Constipation, gastrointestinal distress, nausea
Hypersensitivity: Hypersensitivity reaction (bronchospasm, laryngospasm, cardiovascular collapse)
Ophthalmic: Burning sensation of eyes
Respiratory: Nasal congestion
Concerns related to adverse effects:
- Hypersensitivity reactions: Severe hypersensitivity reactions, including bronchospasm, cardiovascular collapse and laryngospasm have been reported. May be related to localized anesthetic effects due to sucking or chewing the capsule instead of swallowing it.
- Psychiatric effects: Isolated cases of bizarre behavior, including mental confusion and visual hallucinations have been reported during concurrent use with other prescribed drugs.
Special populations:
- Pediatric: Accidental ingestion and potentially fatal overdose of benzonatate has been reported in children <10 years of age. Signs and symptoms of overdose (restlessness, tremors, convulsion, coma, cardiac arrest) may occur within 15 to 20 minutes and death has been reported within 1 hour of ingestion. Not approved for use in children <10 years of age.
C
Animal reproduction studies have not been conducted.
Tetracaine congener with antitussive properties; suppresses cough by topical anesthetic action on the respiratory stretch receptors
Therapeutic: 15 to 20 minutes
3 to 8 hours
- Discuss specific use of drug and side effects with patient as it relates to treatment. (HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand?)
- Patient may experience constipation, dizziness, fatigue, rhinitis, nausea, or headache. Have patient report immediately to prescriber behavioral changes, confusion, hallucinations, or numbness and tingling of mouth, throat, tongue, and face (HCAHPS).
- Educate patient about signs of a significant reaction (eg, wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat). Note: This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions.
Intended Use and Disclaimer: Should not be printed and given to patients. This information is intended to serve as a concise initial reference for health care professionals to use when discussing medications with a patient. You must ultimately rely on your own discretion, experience, and judgment in diagnosing, treating and advising patients.